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The FDA ( Food and Drug Administration ) is warning that the prescription smoking cessation medicine Chantix ( Varenicline ) can change the way people react to alcohol. Interactions between alcohol a ...


The FDA ( Food and Drug Association ) has concluded a review of a study undertaken to determine the cause of elevated levels of the injectable schizophrenia drug Zyprexa Relprevv ( Olanzapine pamoate ...


The FDA ( Food and Drug Administration ) warned that a case of definite progressive multifocal leukoencephalopathy ( PML ) and a case of probable PML have been reported in patients taking Gilenya ( Fi ...


Fumaric acid esters, which are prescribed for the treatment of psoriasis and multiple sclerosis, are considered to have a favorable risk profile. However, treatment-related progressive multifocal leuk ...


Blincyto ( Blinatumomab ) is indicated for the treatment of Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia ( ALL ). This indication is approved ...


Natalizumab ( Tysabri ), a humanized monoclonal antibody, was approved by the Food and Drug Administration ( FDA ) in 2004 on the basis of interim analysis of two phase III studies, AFFIRM and SENTINE ...


Ibuprofen is a non-steroidal anti-inflammatory drug ( NSAID ) used to treat pain, reduce fever, and relieve inflammation. A safety review was initiated by Health Canada following the publication of a ...


FDA ( Food and Drug Administration ) has strengthened the warning for the type 2 diabetes medicine Canagliflozin ( Invokana, Invokamet ) related to the increased risk of bone fractures, and added new ...


The FDA ( Food and Drug Administration ) is strengthening an existing label warning that non-Aspirin nonsteroidal anti-inflammatory drugs ( NSAIDs ) increase the chance of a myocardial infarction or s ...


Case reports and analyses of clinical studies and of pharmacovigilance data suggest that new oral anticoagulants ( NOACs ) are associated with a small risk for hepatotoxicity. The objective of thi ...


The first non-vitamin K antagonist oral anticoagulant ( NOAC ) introduced to the market in Japan was Dabigatran ( Pradaxa ) in March 2011, and three more NOACs, Rivaroxaban ( Xarelto ), Apixaban ( Eli ...


Keytruda ( Pembrolizumab ) is a humanized monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2. By binding to the PD-1 receptor and blocking the interaction wi ...


Topiramate ( Topamax ) is an increasingly used drug during childbearing ages for treatment of epilepsy, migraine, and appetite suppression as well as for off-label indications such as sleep and psychi ...


The FDA ( U.S. Food and Drug Administration ) has warned about reports of severe allergic reactions and herpes zoster associated with the use of Picato gel ( Ingenol mebutate ). Picato is used to ...


Revolade ( Eltrombopag ) is used in adults for the treatment of: • long-term immune thrombocytopenic purpura ( ITP ), a disease in which the patient’s immune system destroys the platelets ( compone ...