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Following completion of a safety review, the TGA ( Therapeutic Goods Administration ) reminds health professionals treating patients with Zolpidem of the risk of next day impairment. Zolpidem ( St ...


Health professionals are reminded of the risks of accidental exposure to or ingestion of Fentanyl patches, especially for children. Fentanyl is an opioid analgesic, interacting predominantly with m ...


Scientific literature suggests a potential association between vascular endothelial growth factor ( VEGF ) receptor inhibition and thrombotic microangiopathy ( TMA ). In certain cases, clinical manif ...


Clopidogrel ( Plavix ) is a platelet aggregation inhibitor indicated for conditions such as myocardial infarction, stroke or established peripheral arterial disease, acute coronary syndrome and atrial ...


A potentially life-threatening condition called drug reaction with eosinophilia and systemic symptoms ( DRESS ) has been reported in patients using Azithromycin, though the number of reports is low. ...


Three published reports ( one Canadian case and two international cases ) have indicated a probable causal association between Quetiapine use and the occurrence of acute liver failure. Two internatio ...


Health Canada has received a published case report of a potential drug-herb interaction between Efavirenz ( Sustiva ) and a Ginkgo biloba product. Efavirenz is a selective non-nucleoside reverse tra ...


The FDA ( Food and Drug Administration ) is warning that injection of corticosteroids into the epidural space of the spine may result in rare but serious adverse events, including loss of vision, stro ...


The FDA ( Food and Drug Administration ) is warning that the insomnia drug Lunesta ( Eszopiclone ) can cause next-day impairment of driving and other activities that require alertness. As a result, ...


The FDA ( Food and Drug Administration ) is warning that certain over-the-counter ( OTC ) topical acne products can cause rare but serious and potentially life-threatening allergic reactions or severe ...


The FDA ( Food and Drug Administration ) is requiring manufacturers to include a general warning in the drug labeling of all approved Testosterone products about the risk of blood clots in the veins. ...


Kyprolis ( Carfilzomib ) for Injection, a proteasome inhibitor, is approved for the treatment of patients with multiple myeloma who have received at least two prior therapies, including Bortezomib and ...


Siltuximab ( Sylvant ) is an anti-interleukin-6 ( IL-6 ) chimeric monoclonal antibody that binds to human IL-6.1 IL-6 is a multifunctional cytokine produced by various cells such as T cells, B cells, ...


Grastek is an allergen extract indicated as immunotherapy for the treatment of grass pollen-induced allergic rhinitis with or without conjunctivitis. Grastek can cause life-threatening allergic rea ...


The FDA ( Food and Drug Administration ) has completed a new study in Medicare patients comparing Pradaxa ( Dabigatran etexilate ) to Warfarin ( Coumadin ), for risk of ischemic or clot-related stroke ...