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PharmAlert Xagena

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Health professionals are reminded of the risks associated with extended or repeated occupational exposure to Methoxyflurane. Methoxyflurane is an anaesthetic that is only approved for short-term us ...


Ivabradine ( Procorolan ) is used to treat symptoms of long-term stable angina in adults with coronary heart disease who have a normal heart rhythm. Ivabradine is also used in patients with long-term ...


Health professionals are advised of the risk of rare but very serious adverse events when using Codeine to treat children after tonsillectomy and/or adenoidectomy. Codeine is a widely used opioid a ...


Health professionals are advised that the Product Information documents for Olmesartan-containing products have been updated with a precaution for sprue-like enteropathy. Olmesartan is a selective ...


Information about the risk of cytomegalovirus reactivation in patients with inflammatory bowel disease has been added to the Product Information for Azathioprine. Azathioprine is used as an immunos ...


A small number of cases of complex regional pain syndrome following vaccination have been reported to the TGA ( Therapeutic Goods Administration ). Health professionals are advised to be mindful of ...


The Product Information ( PI ) for Strontium ranelate has been updated following the completion of a TGA review into the medicine's benefit–risk profile. Strontium ranelate is used to treat severe ...


Following completion of a safety review, the TGA ( Therapeutic Goods Administration ) reminds health professionals treating patients with Zolpidem of the risk of next day impairment. Zolpidem ( St ...


Health professionals are reminded of the risks of accidental exposure to or ingestion of Fentanyl patches, especially for children. Fentanyl is an opioid analgesic, interacting predominantly with m ...


Scientific literature suggests a potential association between vascular endothelial growth factor ( VEGF ) receptor inhibition and thrombotic microangiopathy ( TMA ). In certain cases, clinical manif ...


Clopidogrel ( Plavix ) is a platelet aggregation inhibitor indicated for conditions such as myocardial infarction, stroke or established peripheral arterial disease, acute coronary syndrome and atrial ...


A potentially life-threatening condition called drug reaction with eosinophilia and systemic symptoms ( DRESS ) has been reported in patients using Azithromycin, though the number of reports is low. ...


Three published reports ( one Canadian case and two international cases ) have indicated a probable causal association between Quetiapine use and the occurrence of acute liver failure. Two internatio ...


Health Canada has received a published case report of a potential drug-herb interaction between Efavirenz ( Sustiva ) and a Ginkgo biloba product. Efavirenz is a selective non-nucleoside reverse tra ...


The FDA ( Food and Drug Administration ) is warning that injection of corticosteroids into the epidural space of the spine may result in rare but serious adverse events, including loss of vision, stro ...