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PharmAlert Xagena

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Kyprolis ( Carfilzomib ) for Injection, a proteasome inhibitor, is approved for the treatment of patients with multiple myeloma who have received at least two prior therapies, including Bortezomib and ...


Siltuximab ( Sylvant ) is an anti-interleukin-6 ( IL-6 ) chimeric monoclonal antibody that binds to human IL-6.1 IL-6 is a multifunctional cytokine produced by various cells such as T cells, B cells, ...


Grastek is an allergen extract indicated as immunotherapy for the treatment of grass pollen-induced allergic rhinitis with or without conjunctivitis. Grastek can cause life-threatening allergic rea ...


The FDA ( Food and Drug Administration ) has completed a new study in Medicare patients comparing Pradaxa ( Dabigatran etexilate ) to Warfarin ( Coumadin ), for risk of ischemic or clot-related stroke ...


The Food and Drug Administration ( FDA ) is recommending health care professionals discontinue prescribing and dispensing prescription combination drug products that contain more than 325 mg of Parace ...


Ipilimumab ( Yervoy ) is a novel FDA-approved recombinant human monoclonal antibody that blocks cytotoxic T-lymphocyte antigen-4 ( CTLA-4 ) and has been used to treat patients with metastatic melanoma ...


Systemic antibiotics are a major cause of severe cutaneous adverse reactions ( SCARs ). The selection of alternative antibiotics and management for SCARs patients with underlying infections can be cha ...


In recent years, safety alerts have been made warning of the risk of serious drug-induced liver injury caused by cardiovascular drugs. The new oral anticoagulants ( NOACs ) have now reached the mark ...


The FDA ( Food and Drug Administration ) has requested clinical trial data from the manufacturer of Saxagliptin to investigate a possible association between use of the type 2 diabetes drug and heart ...


The FDA ( Food and Drug Administration ) has concluded that Doribax ( Doripenem ), an antibacterial drug that has been used to treat patients who develop pneumonia while on ventilators, carries an inc ...


Domperidone ( Motilium or other brands ) has modest efficacy against nausea and vomiting. It increases the risk of heart rhythm disorders and sudden death. Based on data on reimbursements paid by the ...


Vimizim ( Elosulfase alfa ) is the first enzyme replacement therapy ( ERT ) designed to target the underlying cause of Morquio A syndrome, a deficiency in the enzyme N-acetylgalactosamine-6 sulfatase ...


Hetlioz, a melatonin receptor agonist, is indicated for the treatment of non-24-hour sleep-wake disorder ( Non-24 ).Important safety informationHetlioz may cause somnolence. After taking Hetlioz, pati ...


The FDA ( Food and Drug Administration ) is investigating the risk of stroke, heart attack, and death in men taking FDA-approved Testosterone products.FDA has decided to reassess this safety issue bas ...


FDA ( Food and Drug Administration ) has warned that the blood pressure drug Olmesartan Medoxomil ( marketed as Benicar, Benicar HCT, Azor, Tribenzor, and generics ) can cause intestinal problems know ...